Six symptoms of depression may herald dementia: new discovery by scientists.

According to ТСН: Scientists from University College London have identified six symptoms of depression that in middle age may indicate an increased risk of developing dementia in the future. The study emphasizes that it is important not only to be aware of the presence of depression but also to pay attention to its specific manifestations.

The study involved 5811 volunteers from the UK. Data regarding their mental state was collected between 1997 and 1999 when the participants were aged between 45 and 69 years, and none of them suffered from dementia. They were observed for nearly 20 years, utilizing official medical records up to 2023.

Throughout this time, dementia was identified in 10.1% of the participants. Among those who reported five or more symptoms of depression in middle age, the risk of developing dementia was 27% higher. The scientists noted that only six out of thirty evaluated symptoms played a key role.

Symptoms that increase risk

• Loss of self-confidence
• Difficulty solving problems
• Absence of a sense of closeness to others
• Constant nervousness
• Problems with concentration
• Dissatisfaction with the quality of daily tasks

The most significant symptoms are considered to be the loss of confidence and difficulties in decision-making – each of these symptoms is associated with approximately a 50% increase in the risk of dementia.

However, some other common manifestations of depression, such as sleep disturbances or suicidal thoughts, did not show a long-term connection with dementia. Researchers note that their study does not assert a direct cause-and-effect relationship but indicates important trends.

Scientists emphasize that their results are based on data from a relatively healthy sample of civil servants in the UK and may not fully reflect the situation in other countries or among different population groups. Nevertheless, these findings could serve as a foundation for further research and the development of earlier and more personalized approaches to the prevention of both depression and neurodegenerative diseases.

This study calls for more attentive attitudes towards mental health since early manifestations of depression may serve as a first signal of potential serious problems in the future. Based on these findings, physicians may better orient themselves in prevention methods and timely assistance for those in need of support.