Gene CCNA2 can heal the heart after a heart attack: scientists' discovery.
Heart recovery thanks to gene CCNA2
According to inkorr.com: The cyclin A2 gene (CCNA2), which switches off after birth, has been found to promote the restoration and distribution of heart cells. This was confirmed by researchers from Mount Sinai Hospital. Experiments demonstrated that activating CCNA2 using a viral vector stimulates the formation of new functional heart tissues, opening new possibilities for the treatment of heart attacks and heart failure.
The impact of age on therapy
People of different ages participated in the study: 21, 41, and 55 years old. The results showed that heart cells in older participants responded to therapy using cyclin A2, whereas the cells of younger individuals did not respond to activation. These findings confirm the natural regenerative capabilities of a young heart.
Prospects for treating heart diseases
Previously, scientists had already demonstrated heart recovery in pigs after a heart attack thanks to CCNA2. The new study suggests that this mechanism can also be successfully used for human cells. As researchers noted, activating CCNA2 stimulates the division of heart cells without disrupting their maturity, paving the way for real heart muscle restoration and shifting from symptom treatment to full recovery.
Thus, scientists believe that the CCNA2 gene may be the key to strengthening the heart muscle after a heart attack, providing new prospects for treating heart diseases in people of different ages. This discovery could significantly change the approaches to rehabilitating patients with heart failure and heart attacks, contributing to the development of more effective treatment methods in the future.
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